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First-trimester tests

First-trimester tests: what to expect
Nine tests, each with a reason.

Short answer

At the first OB appointment, ideally between 6 and 10 weeks, your doctor orders the first-trimester tests: complete blood count, fasting glucose, thyroid function, serologies for infections, blood type and Rh, urinalysis with culture, and an obstetric transvaginal ultrasound. Each one looks for something specific, from anemia and pre-existing diabetes to Rh incompatibility and fetal viability.

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The tests

What each test assesses

TestWhat it assesses
Complete blood countAnemia, infections
Fasting glucosePre-existing diabetes
TSH and free T4Thyroid function
Serologies (HIV, syphilis, hepatitis)Infections with fetal impact
Toxoplasmosis serologyImmunity or risk of infection
Rubella, cytomegalovirus serologyImmunity
Blood type + RhRh incompatibility
Urinalysis + cultureUrinary tract infection
Obstetric transvaginal ultrasoundFetal viability, gestational age

Source: Map to the Positive, Chapter 39.

At the same visit, your OB will discuss genetic testing (NIPT) and the anatomy scan. One of the questions the book suggests you bring is exactly this: which tests are routine and which are optional (genetic)?

The ultrasound depends on timing: from 6 weeks, a transvaginal scan can show the embryo and the heartbeat. Before that there is still little to see, which is one reason the first appointment is best between 6 and 10 weeks. The anatomy scan comes later, usually between 11 and 13 weeks and between 20 and 24 weeks.

More tests, more calm?

Not necessarily. The book warns that frequent ultrasounds and repeated beta-hCGs give relief for 5 minutes and amplify anxiety for hours. Agree with your doctor on which tests are necessary, and stick to them.

The first visit

What happens at the appointment

  1. A complete history: gynecological, medical, family
  2. Confirmation of gestational age
  3. Weight, height and blood pressure
  4. A general physical exam
  5. Transvaginal ultrasound, if you are 6+ weeks, to see the embryo and the heartbeat
  6. Orders for the first-trimester tests
  7. Guidance on supplementation
  8. Guidance on eating, exercise and sexual activity
  9. A discussion about genetic testing (NIPT) and the anatomy scan
  10. Your next appointment scheduled
What to bring

Bring your previous results: they save time

Complete documentation saves time and money, and gives your OB the full picture from the first visit. The book's list:

  • Your beta-hCG results
  • The 11 preconception tests (Station I)
  • Your vaccination record
  • Your complete gynecological history
  • Your history of previous pregnancies, if any
  • A list of current medications
  • A list of current supplements
  • Relevant family history (diabetes, hypertension, genetic conditions)
  • The exact date of your last period
  • Your cycle tracking charts (Station II)
  • Insurance or coverage information
  • Your questions, written down
Where this fits

This is one chapter. The map has 42.

The first-trimester tests are in Chapter 39 of Map to the Positive, in Station V (Positive). The same book opens, in Station I, with the 11 preconception tests, so the results you bring to this appointment can include the ones you did before conceiving. It covers the whole road from preparing to conceive to the first 30 days after a positive, which makes it worth keeping, or giving to someone who is still trying.

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