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Mio Fertility › Station V · Positive
Ectopic pregnancy

Signs of ectopic pregnancy
Suspected ectopic means emergency room.

Short answer

The signs are severe one-sided abdominal pain (usually between 6 and 8 weeks), dark vaginal bleeding, shoulder pain, dizziness, pallor or a rapid heartbeat, and beta-hCG rising slowly. If you suspect an ectopic pregnancy, do not wait for your next appointment: go straight to an emergency room with gynecology services. It occurs in about 2% of pregnancies and is a medical emergency.

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Signs that call for immediate evaluation

  • Severe one-sided abdominal pain, usually between 6 and 8 weeks
  • Dark vaginal bleeding
  • Shoulder pain (a sign of peritoneal irritation from internal bleeding)
  • Dizziness, pallor, rapid heartbeat
  • Beta-hCG rising slowly (less than 35% in 48 hours)
Suspected ectopic = emergency room

If you suspect one, do not wait for your next scheduled appointment. An ectopic can progress to tubal rupture with internal bleeding within hours. Go straight to an emergency room with gynecology services.

The book's short rule: one-sided pain + bleeding = ectopic until proven otherwise. Shoulder pain with any bleeding is also on its list of reasons to go straight to the ER. For anything less clear, call your doctor: one extra call is better than one call too late.

What it is

When the embryo implants outside the uterus

Fertilization happens in the fallopian tube, and the embryo normally travels 5 to 7 days down to the uterus to implant. In an ectopic pregnancy it implants outside the uterus instead, most often in a fallopian tube. It occurs in about 2% of pregnancies, and the book calls it the biggest early concern.

In an ectopic pregnancy, beta-hCG can rise more slowly than the healthy pattern. That is why the book connects ectopic pregnancy to two things you may already be watching: a test that stays negative while your period doesn't come, and a serial beta-hCG that rises less than 35% in 48 hours.

Risk factors

Who should watch more closely

  • A previous ectopic pregnancy
  • A treated STD (chlamydia, gonorrhea)
  • Previous tubal surgery
  • An IUD in place (rare, but possible)
  • Endometriosis
  • Assisted reproduction

What the book suggests if you are at higher risk

  • With a history of ectopic pregnancy, book your first OB appointment earlier, by 6 weeks.
  • Your doctor may order two beta-hCG tests 48 hours apart to check the growth pattern.
  • If your test is negative but your period doesn't come 7 to 10 days after it was due, get a blood beta-hCG.
  • Know the signs above, and do not wait for an appointment if they appear.
Where this fits

This is one chapter. The map has 42.

Ectopic pregnancy is covered in Chapter 40 of Map to the Positive, in Station V (Positive), with the other first-trimester warning signs and a clear list of when to go straight to the ER. The book is the whole map from preparing to conceive through the first 30 days after a positive, including, in Station IV, when to see a specialist and the most common diagnoses. It is worth keeping, or giving to someone who is still trying.

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Related questions

References: ESHRE Guideline on Ectopic Pregnancy, 2020.

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