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Mio Fertility › Station I · Foundation
Medications

Medications to review before trying to conceive
Review them. Don't stop them alone.

Short answer

Some common medications affect fertility or are contraindicated in pregnancy, so any medication in ongoing use needs a mandatory review with your doctor before you try. The rule that comes with it is just as important: don't stop anything on your own. Bring the complete list to your preconception visit.

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The list

Medications that deserve review

The book names five groups to bring to your doctor's attention before trying:

  • Isotretinoin (acne medication): strongly teratogenic
  • Some SSRIs (antidepressants)
  • Non-steroidal anti-inflammatory drugs in continuous use
  • Specific antihypertensives (ACE inhibitors, ARBs)
  • Anticoagulants
Never stop on your own

Several common medications affect fertility or are incompatible with pregnancy, from some antidepressants to acne medications (especially isotretinoin). Never stop medication on your own. Bring the complete list to your preconception visit for review.

Preparing the visit

What to bring to your doctor

The review only works if your doctor sees everything. The book's preparation list for the preconception visit includes:

  • Your medical history: chronic diseases, allergies, medications in use
  • A list of the supplements you already take or plan to take
  • Your family history: genetic diseases, repeated miscarriages, fertility problems

Some medications also change other parts of the plan. Women on anticonvulsants, for example, fall into the book's special cases for folic acid, with a dose of 4 to 5 mg a day instead of the standard 400 to 800 mcg. That is a decision to make with your doctor, and one more reason to bring the full list.

Everyday medications can matter too. The book notes that antihistamines (loratadine, cetirizine) dry out mucous membranes and can leave you with little fertile cervical mucus, and that clomiphene, a medication to induce ovulation, paradoxically thins the mucus. Put them on the list as well.

Mental health

Needing medication is not a reason to stop trying

If you take an antidepressant, the answer is not to drop it on your own. There are antidepressants and anti-anxiety medications compatible with trying to conceive. There is no shame in needing medication to sustain a long journey: mental health is health, full stop. Talk it through with a psychiatrist who understands this context. The same holds after the positive: the book notes there are anxiety medications compatible with pregnancy, prescribed by a psychiatrist who understands this context.

For him, and later

The review doesn't end with you

  • Your partner: the book's self-assessment asks whether he uses anabolic steroids or hormonal supplements, and the book lists steroids among the habits that affect sperm production
  • Before his semen analysis: no recent antibiotics, since some affect the parameters
  • After a positive: stop contraindicated medications, but check with your doctor before stopping anything you take continuously
Where this fits

This is one chapter. The map has 42.

Medications that deserve review close Chapter 10 of Map to the Positive, “The real detox”, in Station I (Foundation), after alcohol, caffeine, tobacco and recreational drugs. Station I also gives you a 20-minute self-assessment that flags ongoing medication use, the 11 preconception tests, smart supplementation, and the preconception visit with a printable question script, so this review happens before you start trying, not after.

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